A systematic-search-and-review of registered pharmacological therapies investigated to improve neuro-recovery after a stroke.

ABSTRACT:

Background

Stroke burden is largely due to long-term impairments requiring prolonged care with loss of productivity. We aimed to identify and assess studies of different registered pharmacological therapies as treatments to improve post-stroke impairments and/or disabilities.

Methods

We performed a systematic-search-and-review of treatments that have been investigated as recovery-enhancing or recovery-promoting therapies in adult patients with stroke. The treatment must have received registration or market authorization in any country regardless of primary indication. Outcomes included in the review were neurological impairments and functional/disability assessments. "The best available studies" based on study design, study size, and/or date of publication were selected and

SUBMITTER: Lee TH 

PROVIDER: S-EPMC10866005 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature