Glucagon fill rates and cost among children and adolescents with type 1 diabetes in the United States, 2011-2021.

ABSTRACT:

Aims

To characterize glucagon fill rates and costs among youth with type 1 diabetes mellitus (T1DM).

Methods

Claims-based analysis of commercially-insured youth with T1DM included in OptumLabs® Data Warehouse between 2011 and 2021. Glucagon fill rates and costs were calculated overall and by formulation (injectable, intranasal, autoinjector, and pre-filled syringe). Sociodemographic and clinical factors associated with glucagon fills were examined using Cox regression.

Results

We identified 13,267 children with T1DM (76.4% non-Hispanic White). Over mean follow-up of 2.81 years (SD 2.62), 70.0% filled glucagon, with stable fill rates from 2011 to 2021. Intranasal glucagon had rapid uptake following initial approval, and it accounted for almost half (46.6%) of all gluca

SUBMITTER: Benning TJ 

PROVIDER: S-EPMC10872944 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature