Proportion of caloric restriction-induced weight loss as skeletal muscle.

ABSTRACT:

Objective

This study's objective was to develop models predicting the relative reduction in skeletal muscle (SM) mass during periods of voluntary calorie restriction (CR) and to validate model predictions in longitudinally monitored samples.

Methods

The model development group included healthy nonexercising adults (n = 897) who had whole-body SM mass measured with magnetic resonance imaging. Model predictions of relative SM changes with CR were evaluated in two longitudinal studies, one 12 to 14 weeks in duration (n = 74) and the other 12 months in duration (n = 26).

Results

A series of SM prediction models were developed in a sample of 415 males and 482 females. Model-predicted changes in SM mass relative to changes in body weight (i.e., ΔSM/Δbody weight) with a repr

SUBMITTER: Heymsfield SB 

PROVIDER: S-EPMC10872987 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature