Manganese Carbonate/Laser-Induced Graphene Composite for Glucose Sensing
Ontology highlight
ABSTRACT:
SUBMITTER: Thakur A
PROVIDER: S-EPMC10882677 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Similar Datasets
Project description:The development of flexible sensors based on laser-induced graphene (LIG) has recently attracted much attention. It was commonly generated by laser-ablating commercial polyimide (PI). However, the weak mechanical extensibility of PI limits the development and diversified applications of LIG-based sensors. In this work, we adopted medical polyurethane (PU) tapes to peel off the LIG generated on PI and developed flexible and wearable sensors based on the proposed LIG/PU composite structure. Compared with other methods for LIG transfer, PU tape has many advantages, including a simplified process and being less time-consuming. We characterized the LIG samples generated under different laser powers and analyzed the property differences introduced by the transfer operation. We then studied the impact of fabrication mode on the strain sensitivity of the LIG/PU and optimized the design of a LIG/PU-based strain sensor, which possessed a gauge factor (GF) of up to 263.6 in the strain range of 75-90%. In addition, we designed a capacitive pressure sensor for tactile sensing, which is composed of two LIG/PU composite structures and a PI space layer. These LIG flexible devices can be used for human motion monitoring and tactile perception in sports events. This work provides a simple, fast, and low-cost way for the preparation of multifunctional sensor systems with good performance, which has a broad application prospect in human motion monitoring.
| S-EPMC10573838 | biostudies-literature
Project description:A simple approach for in situ laser-induced modification of iridium-based materials to increase their electrocatalytic activity towards enzyme-free glucose sensing was proposed. For this purpose, we deposited gold and platinum separately and as a mixture on the surface of pre-synthesized iridium microstructures upon laser irradiation at a wavelength of 532 nm. Then, we carried out the comparative investigation of their morphology, elemental and phase composition as well as their electrochemical properties. The best morphology and, as a result, the highest sensitivity (~9960 µA/mM cm2) with respect to non-enzymatic determination of D-glucose were demonstrated by iridium-gold-platinum microstructures also showing low limit of detection (~0.12 µM), a wide linear range (0.5 µM-1 mM) along with good selectivity, reproducibility and stability.
| S-EPMC7436056 | biostudies-literature
Project description:The reliable detection of ammonia at room temperature is crucial for not only maintaining environmental safety but also for reducing the risks of hazardous pollutants. In this study, the electrochemical modification of laser-induced graphene (LIG) with polyaniline (PANI) led to the development of a chemo-resistive nanocomposite (PANI@LIG) for detecting ammonia levels at room temperature. The composite is characterized by field emission scanning electron microscopy, Fourier transforms infrared, and Raman and X-ray photoelectron spectroscopy. This work marks the first utilization of PANI@LIG for gas sensing and introduces a simple but effective approach for fabricating low-cost wearable gas sensors with high sensitivity and flexibility.
| S-EPMC11644887 | biostudies-literature
Project description:Carbon-based electrodes have demonstrated great promise as electrochemical transducers in the development of biosensors. More recently, laser-induced graphene (LIG), a graphene derivative, appears as a great candidate due to its superior electron transfer characteristics, high surface area and simplicity in its synthesis. The continuous interest in the development of cost-effective, more stable and reliable biosensors for glucose detection make them the most studied and explored within the academic and industry community. In this work, the electrochemistry of glucose oxidase (GOx) adsorbed on LIG electrodes is studied in detail. In addition to the well-known electroactivity of free flavin adenine dinucleotide (FAD), the cofactor of GOx, at the expected half-wave potential of -0.490 V vs. Ag/AgCl (1 M KCl), a new well-defined redox pair at 0.155 V is observed and shown to be related to LIG/GOx interaction. A systematic study was undertaken in order to understand the origin of this activity, including scan rate and pH dependence, along with glucose detection tests. Two protons and two electrons are involved in this reaction, which is shown to be sensitive to the concentration of glucose, restraining its origin to the electron transfer from FAD in the active site of GOx to the electrode via direct or mediated by quinone derivatives acting as mediators.
| S-EPMC8401569 | biostudies-literature
Project description:Laser-induced graphene (LIG) has emerged as a promising electrode material for electrochemical point-of-care diagnostics. LIG offers a large specific surface area and excellent electron transfer at low-cost in a binder-free and rapid fabrication process that lends itself well to mass production outside of the cleanroom. Various LIG micromorphologies can be generated when altering the energy input parameters, and it was investigated here which impact this has on their electroanalytical characteristics and performance. Energy input is well controlled by the laser power, scribing speed, and laser pulse density. Once the threshold of required energy input is reached a broad spectrum of conditions leads to LIG with micromorphologies ranging from delicate irregular brush structures obtained at fast, high energy input, to smoother and more wall like albeit still porous materials. Only a fraction of these LIG structures provided high conductance which is required for appropriate electroanalytical performance. Here, it was found that low, frequent energy input provided the best electroanalytical material, i.e., low levels of power and speed in combination with high spatial pulse density. For example, the sensitivity for the reduction of K3[Fe(CN)6] was increased almost 2-fold by changing fabrication parameters from 60% power and 100% speed to 1% power and 10% speed. These general findings can be translated to any LIG fabrication process independent of devices used. The simple fabrication process of LIG electrodes, their good electroanalytical performance as demonstrated here with a variety of (bio)analytically relevant molecules including ascorbic acid, dopamine, uric acid, p-nitrophenol, and paracetamol, and possible application to biological samples make them ideal and inexpensive transducers for electrochemical (bio)sensors, with the potential to replace the screen-printed systems currently dominating in on-site sensors used.
| S-EPMC8026455 | biostudies-literature
Project description:An integrated polymer-based magnetohydrodynamic (MHD) pump that can actuate saline fluids in closed-channel devices is presented. MHD pumps are attractive for lab-on-chip applications, due to their ability to provide high propulsive force without any moving parts. Unlike other MHD devices, a high level of integration is demonstrated by incorporating both laser-induced graphene (LIG) electrodes as well as a NdFeB magnetic-flux source in the NdFeB-polydimethylsiloxane permanent magnetic composite substrate. The effects of transferring the LIG film from polyimide to the magnetic composite substrate were studied. Operation of the integrated magneto hydrodynamic pump without disruptive bubbles was achieved. In the studied case, the pump produces a flow rate of 28.1 µL/min. while consuming ~1 mW power.
| S-EPMC8037410 | biostudies-literature
Project description:Non-enzymatic glucose sensors outperform enzymatic ones in terms of cost, sensitivity, stability, and operating duration. Though highly sensitive, it is still desirable to further improve the sensitivity of non-enzymatic glucose sensors to detect a trace amount of glucose in sweat and other biofluids. Among the demonstrated effective approaches using bimetals or 3D porous structures, the porous laser-induced graphene (LIG) on flexible polymers showcases good conductivity and a simple fabrication process for the integration of sensing materials. The uniform electroless plating of the nickel and gold layer on LIG electrodes demonstrates significantly enhanced sensitivity and a large linear range for glucose sensing. The sensor with the porous LIG foam exhibits a high sensitivity of 1080 μA mM-1 cm-2, whereas a further increased sensitivity of 3500 μA mM-1 cm-2 is obtained with LIG fibers (LIGF). Impressively, a large linear range (0-30 mM) can be achieved by changing the bias voltage from 0.5 to 0.1 V due to the Au coating. Because the existing non-enzymatic glucose sensors are limited to use in basic solutions, their application in wearable electronics is elusive. In addition to the reduced requirement for the basic solution, this work integrates a porous encapsulating reaction cavity containing alkali solutions with a soft, skin-interfaced microfluidic component to provide integrated microfluidic non-enzymatic glucose sensors for sweat sampling and glucose sensing. The accurate glucose measurements from the human sweat and cell culture media showcase the practical utility, which opens up opportunities for the non-enzymatic glucose sensors in wearable electronics.
| S-EPMC8556579 | biostudies-literature
Project description:The tailoring of novel nanomaterials for sensitive glucose detection through a non-enzymatic mechanism is currently under intensive research. Here, we present a laser-induced graphene (LIG) electrode decorated with silver nanoparticles (AgNPs) as a catalytic element for the direct electrooxidation of glucose. The AgNPs were synthesized through cyclic voltammetry using LIG as a template, resulting in a porous tridimensional assembly with anchored nanostructures. The characterization corroborated the formation of LIG/AgNPs composite with distinctive peaks attributed to Ag2O and AgO interaction with glucose. The proposed non-enzymatic sensors were successfully applied for non-enzymatic amperometric detection, exhibiting a linear range from 1 to 10 mM in the first peak (+0.7 V) and a narrow range from 1 to 2 mM with higher sensitivity of 52.2 mA/mM and improved LOD of 45 μM in the second peak (+0.55 V). The applicability of the LIG/AgNPs sensor was evaluated with spiked artificial saliva in a PoC format using a smartphone potentiostat, showing an average recovery rate of 91%. The analysis was performed in a portable, mobile, and low-cost fashion using a simulated non-invasive sample, with promising results in clinical ranges.
| S-EPMC9954126 | biostudies-literature
Project description:Glyphosate is a globally applied herbicide yet it has been relatively undetectable in-field samples outside of gold-standard techniques. Its presumed nontoxicity toward humans has been contested by the International Agency for Research on Cancer, while it has been detected in farmers' urine, surface waters and crop residues. Rapid, on-site detection of glyphosate is hindered by lack of field-deployable and easy-to-use sensors that circumvent sample transportation to limited laboratories that possess the equipment needed for detection. Herein, the flavoenzyme, glycine oxidase, immobilized on platinum-decorated laser-induced graphene (LIG) is used for selective detection of glyphosate as it is a substrate for GlyOx. The LIG platform provides a scaffold for enzyme attachment while maintaining the electronic and surface properties of graphene. The sensor exhibits a linear range of 10-260 µ m, detection limit of 3.03 µ m, and sensitivity of 0.991 nA µ m -1. The sensor shows minimal interference from the commonly used herbicides and insecticides: atrazine, 2,4-dichlorophenoxyacetic acid, dicamba, parathion-methyl, paraoxon-methyl, malathion, chlorpyrifos, thiamethoxam, clothianidin, and imidacloprid. Sensor function is further tested in complex river water and crop residue fluids, which validate this platform as a scalable, direct-write, and selective method of glyphosate detection for herbicide mapping and food analysis.
| S-EPMC9463521 | biostudies-literature
Project description: Not available
| S-EPMC8496629 | biostudies-literature