Ecological competition in the oral mycobiome of Hispanic adults living in Puerto Rico associates with periodontitis.

ABSTRACT: Background: Fungi are a major component of the human microbiome that only recently received attention. The imbalance of indigenous fungal communities and environmental fungi present in the oral cavity may have a role in oral dysbiosis, which could exacerbate oral inflammatory diseases. Methods: We performed a cross-sectional study and recruited 88 participants aged 21 to 49 from sexually transmitted infection clinics in Puerto Rico. A full-mouth periodontal examination following the NHANES protocol defined periodontal severity (CDC/AAP). ITS2 (fungal) genes were amplified and sequenced for mycobiota characterization of yeast and environmental fungi. Environmental outdoor spore levels were measured daily by the American Academy of Allergy Asthma and Immunology San Juan station

SUBMITTER: Acosta-Pagan K 

PROVIDER: S-EPMC10883086 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature