Aging with a Liver Graft: Analysis of Very Long-Term Survivors after Liver Transplantation.

ABSTRACT:

Background

In Italy, data on long-term survivors after liver transplantation are lacking.

Materials and methods

We conducted a hybrid design study on a cohort of 359 adult recipients who received transplants between 1996 and 2002 to identify predictors of survival and the prevalence of co-morbidities among long-term survivors.

Results

The actuarial (95% CI) patient survival was 96% (94.6-98.3%), 69% (64.2-73.6%), 55% (49.8-59.9%), 42.8% (37.6-47.8%), and 34% (29.2-38.9%) at 1, 5, 10, 15, and 20 years, respectively. The leading causes of death were hepatitis C virus recurrence (24.6%), extrahepatic malignancies (16.9%), infection (14.4%), and hepatocellular carcinoma recurrence (14.4%). The factors associated with the survival probability were younger donor and recipie

SUBMITTER: De Simone P 

PROVIDER: S-EPMC10889074 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature