Acute severe hepatitis of unknown origin in children in Canada.

ABSTRACT:

Background

In spring 2022, a series of reports from the United Kingdom and the United States identified an increase in the incidence of acute severe hepatitis in children. The Public Health Agency of Canada (PHAC) collaborated with provincial/territorial health partners to investigate in Canada. Clinical hepatitis, or inflammation of the liver, is not reportable in Canada, so to determine if an increase was occurring above historical levels, the baseline incidence in Canada was estimated. This article estimates the pre-existing baseline incidence of acute severe hepatitis of unknown origin in children in Canada using administrative databases. It further summarizes the outbreak investigation using information from the national case report forms.

Methods

A committee with repre

SUBMITTER: Macri J 

PROVIDER: S-EPMC10907059 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature