Diagnostic accuracy of magnetically guided capsule endoscopy with a detachable string for detecting oesophagogastric varices in adults with cirrhosis: prospective multicentre study.

ABSTRACT:

Objective

To evaluate the diagnostic accuracy and safety of using magnetically guided capsule endoscopy with a detachable string (ds-MCE) for detecting and grading oesophagogastric varices in adults with cirrhosis.

Design

Prospective multicentre diagnostic accuracy study.

Setting

14 medical centres in China.

Participants

607 adults (>18 years) with cirrhosis recruited between 7 January 2021 and 25 August 2022. Participants underwent ds-MCE (index test), followed by oesophagogastroduodenoscopy (OGD, reference test) within 48 hours. The participants were divided into development and validation cohorts in a ratio of 2:1.

Main outcome measures

The primary outcomes were the sensitivity and specificity of ds-MCE in detecting oesophagogastric varices compared w

SUBMITTER: Jiang X 

PROVIDER: S-EPMC10912951 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature