Association between ambient exposure to PM_2.5 and upper aerodigestive tract cancer in Los Angeles.

ABSTRACT: Fine particulate matter (PM_2.5 ) contains carcinogens similar to those generated by tobacco smoking, which may increase the risks of developing smoking-related cancers, such as upper aerodigestive track (UADT) cancers, for both smokers and never-smokers. Therefore, it is imperative to understand the relation between ambient PM_2.5 exposure and risk of UADT cancers. A population-based case-control study involving 565 incident UADT cancer cases and 983 controls was conducted in Los Angeles County from 1999 to 2004. The average residential PM_2.5 concentration 1 year before the diagnosis date for cases and the reference date for controls was assessed using a chemical transport model. The association between ambient PM_2.5 and the UADT cancers was estim

SUBMITTER: Fang F 

PROVIDER: S-EPMC10932807 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature