Concurrent transmission of multiple carbapenemases in a long-term acute-care hospital.

ABSTRACT:

Objective

We investigated concurrent outbreaks of Pseudomonas aeruginosa carrying bla_VIM (VIM-CRPA) and Enterobacterales carrying bla_KPC (KPC-CRE) at a long-term acute-care hospital (LTACH A).

Methods

We defined an incident case as the first detection of bla_KPC or bla_VIM from a patient's clinical cultures or colonization screening test. We reviewed medical records and performed infection control assessments, colonization screening, environmental sampling, and molecular characterization of carbapenemase-producing organisms from clinical and environmental sources by pulsed-field gel electrophoresis (PFGE) and whole-genome sequencing.

Results

From July 2017 to December 2018, 76 incident cases

SUBMITTER: Rankin DA 

PROVIDER: S-EPMC10933503 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature