Effectiveness of Universal BCG Immunisation in Reducing the Incidence and Mortality of COVID-19: A Secondary Data Analysis.

ABSTRACT:

Background

Bacillus Calmette-Guérin (BCG) vaccine's immunomodulatory properties can protect against respiratory infections due to its nonspecific trained immunity of innate immune cells. The objective of the study is to assess the effectiveness of BCG in reducing incidence and morality of ongoing COVID-19 pandemic.

Methodology

The present study is a secondary data analysis to compare the incidence and mortality of COVID 19 among countries who had BCG vaccine in their national immunisation schedule with other group of countries who did not have. Twenty-six countries with BCG vaccinations and eleven countries without BCG vaccinations were included in the analysis. The analysis was performed using the glmer() function in R and a random effects logistic model to study the determ

SUBMITTER: Bhatia V 

PROVIDER: S-EPMC10937066 | biostudies-literature | 2021 Mar-Apr

REPOSITORIES: biostudies-literature