Mechanism and treatment of diarrhea associated with tyrosine kinase inhibitors.
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SUBMITTER: Liu J
PROVIDER: S-EPMC10945189 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
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Mechanism and treatment of diarrhea associated with tyrosine kinase inhibitors.
Liu Jiangnan J Yan Shuai S Du Juntong J Teng Lizhi L Yang Ru R Xu Peng P Tao Weiyang W
Heliyon 20240306 6
Tyrosine kinase inhibitors (TKIs) have become first-line drugs for cancer treatment. However, their clinical use is seriously hindered since many patients experience diarrhea after receiving TKIs. The mechanisms of TKI-associated diarrhea remain unclear. Most existing therapies are symptomatic treatments based on experience and their effects are unsatisfactory. Therefore, clarification of the mechanisms underlying diarrhea is critical to develop effective anti-diarrhea drugs. This article summar ...[more]
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