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Impact of a syndrome-based stewardship intervention on antipseudomonal beta-lactam use, antimicrobial resistance, C. difficile rates, and cost in a safety-net community hospital.

ABSTRACT: Broad-spectrum antimicrobials are commonly used without indication and contribute to antimicrobial resistance (AMR). We implemented a syndrome-based stewardship intervention in a community hospital that targeted common infectious syndromes and antipseudomonal beta-lactam (APBL) use. Our intervention successfully reduced AMR, C. difficile rates, use of APBLs, and cost.

SUBMITTER: Mena Lora AJ 

PROVIDER: S-EPMC10945933 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature

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Impact of a syndrome-based stewardship intervention on antipseudomonal beta-lactam use, antimicrobial resistance, <i>C. difficile</i> rates, and cost in a safety-net community hospital.

Mena Lora Alfredo J AJ   Burgos Rodrigo R   Hunt Aaron E AE   Wang Yifan Y   Huber Dylan D   Sanchez Lawrence L   Ali Mirza M   Krill Candice C   Takhsh Eden E   Bleasdale Susan C SC  

Antimicrobial stewardship & healthcare epidemiology : ASHE 20240313 1

Broad-spectrum antimicrobials are commonly used without indication and contribute to antimicrobial resistance (AMR). We implemented a syndrome-based stewardship intervention in a community hospital that targeted common infectious syndromes and antipseudomonal beta-lactam (APBL) use. Our intervention successfully reduced AMR, <i>C. difficile</i> rates, use of APBLs, and cost. ...[more]

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