Nanopartikel auf subnanometer dunnen oxidischen Filmen: Skalierung von Modellsystemen
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ABSTRACT:
SUBMITTER: Ament K
PROVIDER: S-EPMC10946923 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
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| S-EPMC10947009 | biostudies-literature
Project description:Purpose To review the sustained effect of COVID-19 on rhegmatogenous retinal detachment (RRD) baseline characteristics and outcomes. Methods This was a retrospective consecutive case series at the Birmingham and Midlands Eye Centre including patients undergoing primary RRD repair between 23 March and 31 December 2017–2019 (Group 1) and 2020 (Group 2). The deciles of indices of multiple deprivation (IMD) were determined by postcode to group patients into least deprived (IMD1-5) and most deprived (IMD6-10). Results In total we reviewed 1310 patients, 1003 in Group 1 and 307 in Group 2. Relative to 2017–2019, during the first lockdown, we observed (a) a reduction in the number of patients with RRD, (b) an increase in macula-off detachments, (c) an increase in RRD primary failure, and (d) that the least deprived had proportionately higher primary failure than the most deprived (p = 0.049) with a higher detachment rate than the pre-COVID-19 period (p = 0.010) and increased presentations of macula-off detachment. During the second lockdown, these differences were not observed. Conclusion The previously observed findings of lower presentation rates of RRD during the beginning of the first lockdown and the decreased number of macula-on RRD were not sustained over a longer period of observation or found to recur after a second national lockdown. Patients from areas with the least socioeconomic deprivation seemed to be more negatively affected by the first lockdown, with later presentation and higher rates of re-detachments compared with the most deprived during the first lockdown. Our findings offer reassurance that patient behaviour and health services had adapted to the pandemic by the second national lockdown. Supplementary Information The online version of this article (10.1007/s00717-022-00521-0) contains supplementary material, which is available to authorized users.
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Project description:Hintergrund Seit Beginn der COVID-19-Pandemie mehren sich Befunde zu ihrem negativen Einfluss auf die psychische Gesundheit von Kindern und Jugendlichen. Bisher ist jedoch wenig darüber bekannt, ob und wie sich dies auf die psychotherapeutische Versorgung von Kindern und Jugendlichen niederschlägt. Ziel der Arbeit Die psychische Situation von Kindern und Jugendlichen sowie ihre psychotherapeutische Versorgung seit Beginn der COVID-19-Pandemie sollen aus Sicht von Kinder- und JugendlichenpsychotherapeutInnen (KJP) erfasst werden. Material und Methoden Es wurden 324 KJP aus Deutschland in einer Online-Umfrage gebeten, die letzten 6 Monate mit einem 6‑monatigen Zeitraum vor 2 Jahren zu vergleichen. Fünf- und 7‑stufige Likert-Skalen, Fragen mit Mehr- und Einfachauswahl sowie numerische und ein freies Antwortformat wurden verwendet. Ergebnisse Seit Pandemiebeginn haben sich die Wartezeiten nahezu verdoppelt. Es werden mehr Behandlungsstunden angeboten, v. a. mehr Erstgespräche durchgeführt. Therapieverlängerungen kommen häufiger, -abbrüche seltener vor. Bei der Hälfte der PatientInnen ist eine pandemieassoziierte Symptomverschlechterung aufgetreten. Alle erfragten psychischen Störungen treten z. T. deutlich häufiger auf (v. a. Depressionen, Angststörungen, Medienabhängigkeit, Schlaf‑, Anpassungs‑, Zwangs- und Essstörungen). Es erfolgen mehr Telefon- und Videositzungen als vor der Pandemie. Die Zusammenarbeit mit Eltern hat sich verstärkt, die mit dem interdisziplinären Netzwerk verringert. Diskussion Die Pandemie hat einen deutlichen Einfluss auf die psychische Verfassung und die psychotherapeutische Versorgung von Kindern und Jugendlichen in Deutschland. Eine Anpassung des Versorgungssystems an den gestiegenen Bedarf wird vorgeschlagen, um mögliche Folgeschäden der Pandemie zu begrenzen. Zusatzmaterial online Die Online-Version dieses Beitrags (10.1007/s00278-022-00604-y) enthält die detaillierten Fragen des Fragebogens.
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