Unveiling the challenges of UTUC biopsies and cytology: insights from a global real-world practice study.

ABSTRACT:

Purpose

Diagnostic ureteroscopy (dURS) is optional in the assessment of patients with upper tract urothelial carcinoma (UTUC) and provides the possibility of obtaining histology.

Methods

To evaluate endoscopic biopsy techniques and outcomes, we assessed data from patients from the CROES-UTUC registry. The registry includes multicenter prospective collected data on diagnosis and management of patients suspected having UTUC.

Results

We assessed 2380 patients from 101 centers. dURS with biopsy was performed in 31.6% of patients. The quality of samples was sufficient for diagnosis in 83.5% of cases. There was no significant association between biopsy techniques and quality (p = 0.458). High-grade biopsy accurately predicted high-grade disease in 95.7% and high-risk stage

SUBMITTER: Baard J 

PROVIDER: S-EPMC10954852 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature