Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke.

ABSTRACT:

Background

Computed tomography perfusion (CTP)-estimated core volume is associated with functional outcomes in acute ischemic stroke. This relationship might differ among patients, depending on brain volume.

Materials and methods

We retrospectively included patients from the MR CLEAN Registry. Cerebrospinal fluid (CSF) and intracranial volume (ICV) were automatically segmented on NCCT. We defined the proportion of the ICV and total brain volume (TBV) affected by the ischemic core as ICV_core and TBV_core. Associations between the core volume, ICV_core, TBV_core, and functional outcome are reported per interquartile range (IQR). We calculated the area under the curve (AUC) to assess diagnostic accuracy.

Results

In 200 patients, t

SUBMITTER: Hoving JW 

PROVIDER: S-EPMC10971384 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature