Dataset Information

Relationship between educational level and survival of patients with cancer: A multicentre cohort study.

ABSTRACT:

Background

Although socioeconomic factors are important determinants of population mortality, the effect of educational level on the survival of patients with cancer in China is unclear. This study aimed to assess whether educational level is associated with the prognosis of patients with cancer and to explore the mediators of this association.

Methods

This multicentre cohort study included 18,251 patients diagnosed with cancer between May 2013 and December 2018. The main parameters measured were overall survival (OS) and all-cause mortality. The relationship between educational level and all-cause mortality was assessed using multifactor-corrected Cox survival analysis. Logistic regression was used to analyze the association between educational level and patient-generated subjective global assessment (PG-SGA).

Results

The mean age of the 18,251 participants (men, 9939 [54.4%]) was 57.37 ± 11.66 years. Multifactorial survival analysis showed that patients survived longer with increasing education (university and above vs. elementary school and below; p = p = <0.001, HR = 0.84, 95% CI: 0.77-0.92), and the differences were statistically significant in different subgroups. The potential impact factors included sex, age, TNM stage, and PG-SGA score. Logistic regression showed a significant negative association between educational level and the modifiable factor PG-SGA (secondary vs. primary and below; p = 0.004, HR = 0.90, 95% CI: 0.83-0.97; university and above vs. primary and below; p < 0.001, HR = 0.79, 95% CI: 0.71-0.88).

Conclusions

Educational level was a significant prognostic factor for patients with cancer, independent of other known prognostic factors. This association was further improved by modifying the nutritional status.

SUBMITTER: Liu XY

PROVIDER: S-EPMC10974719 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

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Publications

Relationship between educational level and survival of patients with cancer: A multicentre cohort study.

Liu Xiao-Yue XY Zhang Xi X Ruan Guo-Tian GT Zheng Xin X Chen Yue Y Zhang Xiao-Wei XW Liu Tong T Ge Yi-Zhong YZ Shi Han-Ping HP

Cancer medicine 20240401 7

<h4>Background</h4>Although socioeconomic factors are important determinants of population mortality, the effect of educational level on the survival of patients with cancer in China is unclear. This study aimed to assess whether educational level is associated with the prognosis of patients with cancer and to explore the mediators of this association.<h4>Methods</h4>This multicentre cohort study included 18,251 patients diagnosed with cancer between May 2013 and December 2018. The main paramete ...[more]

PMID: 38545856

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Dataset Information

Relationship between educational level and survival of patients with cancer: A multicentre cohort study.

Background

Methods

Results

Conclusions

Publications

Relationship between educational level and survival of patients with cancer: A multicentre cohort study.

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