Beneficial effects of bioinspired silver nanoparticles on zebrafish embryos including a gene expression study.

ABSTRACT:

Background and purpose

Many sectors use nanoparticles and dispose of them in the aquatic environment without deciding the fate of these particles.

Experimental approach

To identify a benign species of nanoparticles which can cause minimum harm to the aquatic environment, a comparative study was done with chemically synthesized silver nanoparticles (AgNPs) and green tea mediated synthesis (GT/AgNP) in both in vitro using human alveolar cancer cell line (A549) and normal cell line (L132), and in in vivo with zebrafish embryos.

Key results

The in vitro studies revealed that GT/AgNPs were less toxic to normal cells than cancer cells. The GT/AgNPs showed high biocompatibility for zebrafish embryos monitored microscopically for their developmental stages and by cumulative h

SUBMITTER: R SD 

PROVIDER: S-EPMC10974822 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature