Short-term recovery of insulin secretion in response to a meal is associated with future glycemic control in type 2 diabetes patients.

ABSTRACT:

Aims/introduction

Endogenous insulin secretion could be recovered by improving hyperglycemia in patients with type 2 diabetes. This study aimed to investigate the association between short-term recovery of insulin secretion during hospitalization and clinical background or future glycemic control in patients with type 2 diabetes.

Materials and methods

A total of 127 patients with type 2 diabetes were included. The recovery of endogenous insulin secretion was determined using the following indices: index A: fasting C-peptide index (CPI) at discharge - fasting CPI on admission; index B: postprandial CPI at discharge - postprandial CPI on admission; and index C: Δ C-peptide immunoreactivity (CPR) (postprandial CPR - fasting CPR) at discharge - ΔCPR on admission. We examined the

SUBMITTER: Enkaku A 

PROVIDER: S-EPMC10981139 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature