Carriage of Haemophilus influenzae serotype A in children: Canadian Immunization Research Network (CIRN) study.

ABSTRACT:

Background

Haemophilus influenzae serotype a (Hia) has recently emerged as an important cause of invasive disease, mainly affecting young Indigenous children. Carriage of H. influenzae is a pre-requisite for invasive disease and reservoir for transmission. To better understand the epidemiology of invasive Hia disease, we initiated a multicentre study of H. influenzae nasopharyngeal carriage among Canadian children.

Methods

With prior parental consent, we collected nasotracheal tubes used during general anaesthesia in healthy children following routine dental surgery in a regional hospital of northwestern Ontario and a dental clinic in central Saskatchewan. In northwestern Ontario, all children were Indigenous (median age 48.0 months, 45.8% female); in Sa

SUBMITTER: Ulanova M 

PROVIDER: S-EPMC10984318 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature