Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer.

ABSTRACT:

Importance

The association of tumor-infiltrating lymphocyte (TIL) abundance in breast cancer tissue with cancer recurrence and death in patients with early-stage triple-negative breast cancer (TNBC) who are not treated with adjuvant or neoadjuvant chemotherapy is unclear.

Objective

To study the association of TIL abundance in breast cancer tissue with survival among patients with early-stage TNBC who were treated with locoregional therapy but no chemotherapy.

Design, setting, and participants

Retrospective pooled analysis of individual patient-level data from 13 participating centers in North America (Rochester, Minnesota; Vancouver, British Columbia, Canada), Europe (Paris, Lyon, and Villejuif, France; Amsterdam and Rotterdam, the Netherlands; Milan, Padova, and Geno

SUBMITTER: Leon-Ferre RA 

PROVIDER: S-EPMC10988354 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature