PyCoMo: a python package for community metabolic model creation and analysis.

ABSTRACT:

Summary

PyCoMo is a python package for quick and easy generation of genome-scale compartmentalized community metabolic models that are compliant with current openCOBRA file formats. The resulting models can be used to predict (i) the maximum growth rate at a given abundance profile, (ii) the feasible community compositions at a given growth rate, and (iii) all exchange metabolites and cross-feeding interactions in a community metabolic model independent of the abundance profile; we demonstrate PyCoMo's capability by analysing methane production in a previously published simplified biogas community metabolic model.

Availability and implementation

PyCoMo is freely available under an MIT licence at http://github.com/univieCUBE/PyCoMo, the Python Package Index, and Zenodo.

SUBMITTER: Predl M 

PROVIDER: S-EPMC10990682 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature