Ontology highlight
ABSTRACT:
SUBMITTER: Hybiske K
PROVIDER: S-EPMC11003224 | biostudies-literature | 2024 Apr
REPOSITORIES: biostudies-literature
Hybiske Kevin K Paktinat Shahrokh S Newman Katherine K Patton Dorothy D Khosropour Christine C Roxby Alison C AC Mugo Nelly R NR Oluoch Lynda L Ngure Kenneth K Suchland Robert R Hladik Florian F Vojtech Lucia L
Infection and immunity 20240307 4
Non-neutralizing functions of antibodies, including phagocytosis, may play a role in <i>Chlamydia trachomatis</i> (CT) infection, but these functions have not been studied and assays are lacking. We utilized a flow-cytometry-based assay to determine whether serum samples from a well-characterized cohort of CT-infected and naïve control individuals enhanced phagocytosis via Fc-receptor-expressing THP-1 cells, and whether this activity correlated with antibody titers. Fc-receptor-mediated phagocyt ...[more]