Metabolic Comparison and Molecular Networking of Antimicrobials in Streptomyces Species.

ABSTRACT: Streptomyces are well-known for producing bioactive secondary metabolites, with numerous antimicrobials essential to fight against infectious diseases. Globally, multidrug-resistant (MDR) microorganisms significantly challenge human and veterinary diseases. To tackle this issue, there is an urgent need for alternative antimicrobials. In the search for potent agents, we have isolated four Streptomyces species PC1, BT1, BT2, and BT3 from soils collected from various geographical regions of the Himalayan country Nepal, which were then identified based on morphology and 16S rRNA gene sequencing. The relationship of soil microbes with different Streptomyces species has been shown in phylogenetic trees. Antimicrobial potency of isolates was carried out against Staphylococ

SUBMITTER: Thapa BB 

PROVIDER: S-EPMC11050201 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature