Developing a platform for secretion of biomolecules in Mycoplasma feriruminatoris.

ABSTRACT:

Background

Having a simple and fast dividing organism capable of producing and exposing at its surface or secreting functional complex biomolecules with disulphide bridges is of great interest. The mycoplasma bacterial genus offers a set of relevant properties that make it an interesting chassis for such purposes, the main one being the absence of a cell wall. However, due to their slow growth, they have rarely been considered as a potential platform in this respect. This notion may be challenged with the recent discovery of Mycoplasma feriruminatoris, a species with a dividing time close to that of common microbial workhorses. So far, no tools for heterologous protein expression nor secretion have been described for it.

Results

The work presented here develops the fast-divi

SUBMITTER: Gonzalez-de-Miguel J 

PROVIDER: S-EPMC11059754 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature