Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study.

ABSTRACT:

Objectives

To estimate the incidence of adverse events of interest (AEIs) after receiving their first and second doses of coronavirus disease 2019 (COVID-19) vaccinations, and to report the safety profile differences between the different COVID-19 vaccines.

Design

We used a self-controlled case series design to estimate the relative incidence (RI) of AEIs reported to the Oxford-Royal College of General Practitioners national sentinel network. We compared the AEIs that occurred seven days before and after receiving the COVID-19 vaccinations to background levels between 1 October 2020 and 12 September 2021.

Setting

England, UK.

Participants

Individuals experiencing AEIs after receiving first and second doses of COVID-19 vaccines.

Main outcome measures

AEIs

SUBMITTER: Tsang RS 

PROVIDER: S-EPMC11100448 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature