Long-Term Outcomes in Patients Using Protocol-Directed Active Surveillance for Prostate Cancer.

ABSTRACT:

Importance

Outcomes from protocol-directed active surveillance for favorable-risk prostate cancers are needed to support decision-making.

Objective

To characterize the long-term oncological outcomes of patients receiving active surveillance in a multicenter, protocol-directed cohort.

Design, setting, and participants

The Canary Prostate Active Surveillance Study (PASS) is a prospective cohort study initiated in 2008. A cohort of 2155 men with favorable-risk prostate cancer and no prior treatment were enrolled at 10 North American centers through August 2022.

Exposure

Active surveillance for prostate cancer.

Main outcomes and measures

Cumulative incidence of biopsy grade reclassification, treatment, metastasis, prostate cancer mortality, overall mortality

SUBMITTER: Newcomb LF 

PROVIDER: S-EPMC11140579 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature