Effects of endogenous testosterone on oscillatory activity during verbal working memory in youth.

ABSTRACT: Testosterone levels sharply rise during the transition from childhood to adolescence and these changes are known to be associated with changes in human brain structure. During this same developmental window, there are also robust changes in the neural oscillatory dynamics serving verbal working memory processing. Surprisingly, whereas many studies have investigated the effects of chronological age on the neural oscillations supporting verbal working memory, none have probed the impact of endogenous testosterone levels during this developmental period. Using a sample of 89 youth aged 6-14 years-old, we collected salivary testosterone samples and recorded magnetoencephalography during a modified Sternberg verbal working memory task. Significant oscillatory responses were identified and image

SUBMITTER: Killanin AD 

PROVIDER: S-EPMC11215982 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature