Sustained inflation and chest compression versus 3:1 chest compression to ventilation ratio during cardiopulmonary resuscitation of asphyxiated newborns (SURV1VE): A cluster randomised controlled trial.

ABSTRACT:

Objective

In newborn infants requiring chest compression (CC) in the delivery room (DR) does continuous CC superimposed by a sustained inflation (CC+SI) compared with a 3:1 compression:ventilation (3:1 C:V) ratio decreases time to return of spontaneous circulation (ROSC).

Design

International, multicenter, prospective, cluster cross-over randomised trial.

Setting

DR in four hospitals in Canada and Austria, PARTICIPANTS: Newborn infants >28 weeks' gestation who required CC.

Interventions

Hospitals were randomised to CC+SI or 3:1 C:V then crossed over to the other intervention.

Main outcome measure

The primary outcome was time to ROSC, defined as the duration of CC until an increase in heart rate >60/min determined by auscultation of the heart, which was m

SUBMITTER: Schmolzer GM 

PROVIDER: S-EPMC11228189 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature