MMP11 as a prognostic biomarker correlated with immune infiltrates in pancreatic adenocarcinoma.

ABSTRACT:

Background

Matrix metalloproteinase 11 (MMP11) plays a vital role in cell proliferation, apoptosis, tumor angiogenesis, migration, and other basic processes. Currently, few studies have examined the value of MMP11 in pancreatic cancer in relation to prognostic risk, diagnostic indicators, and immunotherapy. This study aims to explore the association between MMP11 and the tumor immune microenvironment in pancreatic adenocarcinoma (PAAD).

Methods

We selected clinical samples and data downloaded from The Cancer Genome Atlas and Genotype-Tissue Expression, in addition, we use other online data for further analysis. Through a comprehensive bioinformatics investigation, we systematically analyzed the clinical significance and expression level of MMP11 in pancr

SUBMITTER: Fang Z 

PROVIDER: S-EPMC11231847 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature