Safety and efficacy of danazol in immune thrombocytopenia: a systematic review.

ABSTRACT:

Background

The treatment landscape for relapsed or refractory immune thrombocytopenia (ITP) after corticosteroids is complex.

Objectives

We aimed to assess the efficacy of danazol in treating ITP and evaluate the safety and adverse events following its administration.

Methods

We searched the databases PubMed, EMBASE, and ClinicalTrials.gov for all published studies assessing danazol's efficacy and safety in treating ITP. The retrieved studies were screened by title and abstract, followed by full-text screening based on the eligibility requirements. The quality assessment was performed using a set of questionnaires. The data were extracted on the descriptive characteristics of the studies and participants, drug dosage, efficacy measures, and adverse effects, and the da

SUBMITTER: Shah S 

PROVIDER: S-EPMC11234045 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature