Individualized trajectories in postradiotherapy neurocognitive functioning of patients with brain metastases.

ABSTRACT:

Background

The increasing incidence of brain metastases (BMs) and improved survival rates underscore the necessity to investigate the effects of treatments on individuals. The aim of this study was to evaluate the individual trajectories of subjective and objective cognitive performance after radiotherapy in patients with BMs.

Methods

The study population consisted of adult patients with BMs referred for radiotherapy. A semi-structured interview and comprehensive neurocognitive assessment (NCA) were used to assess both subjective and objective cognitive performance before, 3 months and ≥ 11 months after radiotherapy. Reliable change indices were used to identify individual, clinically meaningful changes.

Results

Thirty-six patients completed the 3-month follow-up, and

SUBMITTER: van Grinsven EE 

PROVIDER: S-EPMC11241367 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature