A Label-Free Photoelectrochemical Biosensor Based on ZnO/Cs3MnBr5 Heterogeneous Films for Alpha-Fetoprotein Detection.
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ABSTRACT: Highly sensitive and specific biomarker detection is of outstanding importance for the diagnosis and treatment of cancers. Herein, we developed robust photoelectrochemical (PEC) biosensors with low background noise and high sensitivity based on a heterojunction, which can improve semiconductor photoelectric properties by limiting the recombination of photogenerated electron-hole pairs and successfully widening the range of light absorption. Alpha-fetoprotein (AFP) was used as a target model to examine the analytical performances of the designed PEC biosensors. ZnO/Cs3MnBr5 heterogeneous film with a uniform porous structure and large surface area enhanced electron transfer and biomolecule immobilization, and significantly increased the photocurrent response. Under the
SUBMITTER: Shao L
PROVIDER: S-EPMC11243747 | biostudies-literature | 2024 Jun
REPOSITORIES: biostudies-literature
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