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Characteristic Skin Eruptions with a Distinct Histological Pattern Allow Early Diagnosis of Vitamin C Deficiency.


ABSTRACT:

Introduction

Scurvy has become a rare disease in western countries with potentially high morbidity. Early diagnosis is crucial and can be challenging.

Case presentation

We present the case of a 56-year-old male patient who developed hemorrhagic diathesis after trivial impact trauma. Previously, the patient suffered from fatigue and loss of appetite. Characteristic skin eruptions and a distinct skin histology along with a decreased serum vitamin C level led to the diagnosis of scurvy. Following vitamin C supplementation, symptoms improved rapidly.

Conclusion

In conclusion, vitamin C deficiency should be considered in cases with unclear hemorrhagic diathesis and a medical history of nutritional irregularities. Especially in cases of scurvy that do not yet show the full clinical spectrum of symptoms or have only moderately decreased serum vitamin C levels, thorough clinical dermatological examination and a skin biopsy are essential for early diagnosis and to prevent complications.

SUBMITTER: Mirkovic G 

PROVIDER: S-EPMC11249473 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature

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Characteristic Skin Eruptions with a Distinct Histological Pattern Allow Early Diagnosis of Vitamin C Deficiency.

Mirkovic Goran G   Mutke Markus Reinhold MR   Muehleisen Beda B  

Case reports in dermatology 20240101 1


<h4>Introduction</h4>Scurvy has become a rare disease in western countries with potentially high morbidity. Early diagnosis is crucial and can be challenging.<h4>Case presentation</h4>We present the case of a 56-year-old male patient who developed hemorrhagic diathesis after trivial impact trauma. Previously, the patient suffered from fatigue and loss of appetite. Characteristic skin eruptions and a distinct skin histology along with a decreased serum vitamin C level led to the diagnosis of scur  ...[more]

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