Prophylactic Intravenous Aminophylline for Preventing Bradyarrhythmias During Coronary Atherectomy: A 10-Year Single-Center Experience.

ABSTRACT:

Background

Aminophylline, an adenosine antagonist, can be used to prevent adenosine-mediated bradyarrhythmias.

Methods

Retrospective, observational, descriptive analysis of patients undergoing rotational atherectomy with intravenous (IV) aminophylline pretreatment during a 10-year period (2010-2020). The primary composite outcome was the occurrence of a documented bradyarrhythmia requiring pharmacologic intervention and/or temporary pacemaker (TPM) implantation.

Results

A total of 296 patients received IV aminophylline pretreatment. The primary composite outcome occurred in 1.7% (n = 5) of patients. None of the patients required rescue TPM. Bradyarrhythmias were documented in 2.4% (n = 7) of patients. Pharmacologic interventions, typically with IV atropine, were used

SUBMITTER: Knott JD 

PROVIDER: S-EPMC11308821 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature