Detection of microemboli in patients with acute ischaemic stroke and atrial fibrillation suggests poor functional outcome.

ABSTRACT:

Introduction

We investigated the burden of microembolic signals (MES) in patients with acute ischaemic stroke (AIS) and atrial fibrillation (AF), assessing their impact on functional outcomes.

Patients and methods

This multicentre international prospective cohort study involved patients with AIS and either a known or newly diagnosed anticoagulant-naïve AF. All centres utilised the same transcranial Doppler machine for 1-h monitoring with bilateral 2 MHz probes within 24 h of symptom onset. Recordings underwent MES analysis by a blinded central reader. The primary objectives were to ascertain the MES proportion and its association with functional outcomes assessed by the modified Rankin scale (mRS) score at 90 days.

Results

Between September 2019 and May 2021, we enrol

SUBMITTER: Castro P 

PROVIDER: S-EPMC11318424 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature