Diffusion-based virtual MR elastography for predicting recurrence of solitary hepatocellular carcinoma after hepatectomy.

ABSTRACT:

Background

To explore the capability of diffusion-based virtual MR elastography (vMRE) in the preoperative prediction of recurrence in hepatocellular carcinoma (HCC) and to investigate the underlying relevant histopathological characteristics.

Methods

Between August 2015 and December 2016, patients underwent preoperative MRI examination with a dedicated DWI sequence (b-values: 200,1500 s/mm²) were recruited. The ADC values and diffusion-based virtual shear modulus (μ_diff) of HCCs were calculated and MR morphological features were also analyzed. The Cox proportional hazards model was used to identify the risk factors associated with tumor recurrence. A preoperative radiologic model and postoperative model including pathological features were built to pre

SUBMITTER: Chen J 

PROVIDER: S-EPMC11320769 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature