Sitting knee-flexion angle does not influence endothelial-dependent vasodilation in laboratory or free-living conditions.

ABSTRACT:

Introduction

Single bouts of prolonged bent-legged sitting attenuate popliteal endothelial-dependent vasodilation (as assessed via flow-mediated dilation [FMD]), which is partially attributed to arterial 'kinking'. However, the impact of knee-flexion angle on sitting-induced popliteal FMD is unknown. The objective of this study was to perform separate laboratory and free-living studies to test the hypotheses that: (1) popliteal FMD impairments would be graded between knee flexions at 90° (bent-legged sitting) > 45° > 0° (straight-legged sitting) following a 3-hour bout of sitting; and (2) more habitual time spent bent-legged sitting (< 45°) would be associated with lower FMD.

Methods

The laboratory study included eight young, healthy adults (24 ± 2 years; four women) who und

SUBMITTER: Shivgulam ME 

PROVIDER: S-EPMC11323422 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature