Dataset Information

Nonrestorative Sleep and Type 2 Diabetes Incidence: the Aichi Workers' Cohort Study.

ABSTRACT:

Background

The term "nonrestorative sleep (NRS)" refers to unrefreshed feeling at wake-up and is a domain of poor sleep quality. Previous researches have demonstrated that NRS is linked to a number of diseases and adverse health outcomes, but less is known regarding the link between NRS and diabetes, particularly in Japanese.

Methods

We studied 3665 middle-aged male participants of the Aichi Workers' Cohort Study who were followed-up from 2002 to 2019. Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) of incident type 2 diabetes mellitus (T2DM) in relation to NRS adjusted for potential confounding variables.

Results

During a median follow-up of 14.6 years, 421 type 2 diabetes cases were identified. Participants with NRS had a higher crude incidence rate of T2DM (11.2/1,000 person-years), compared to participants without NRS (9.3/1,000 person-years). In the fully adjusted model, individuals who reported having NRS had a significantly higher risk of developing T2DM (HR: 1.36, 95% CI: 1.10-1.67). The association was observed only in participants under 50 years old (HR: 1.82, 95% CI: 1.36-2.43), not in the older (50 years or older) participants (P for interaction =0.025). In contrast, stratified analyses by the presence of shift work, obesity or sleep duration showed similar associations in all the strata.

Conclusions

NRS was associated with higher risk of T2DM in middle-aged Japanese male workers independent of a variety of lifestyle factors and other sleep problems.

SUBMITTER: Lin J

PROVIDER: S-EPMC11330709 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature

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Publications

Nonrestorative Sleep and Type 2 Diabetes Incidence: The Aichi Workers' Cohort Study.

Lin Jingyi J Song Zean Z Li Yuanying Y Chiang Chifa C Hirakawa Yoshihisa Y Nakano Yoshihisa Y Hong Young-Jae YJ Matsunaga Masaaki M Ota Atsuhiko A Tamakoshi Koji K Yatsuya Hiroshi H

Journal of epidemiology 20240127 9

<h4>Background</h4>The term "nonrestorative sleep (NRS)" refers to an unrefreshed feeling at wake-up and is a domain of poor sleep quality. Previous research has demonstrated that NRS is linked to a number of diseases and adverse health outcomes, but less is known regarding the link between NRS and diabetes, particularly in Japanese.<h4>Methods</h4>We studied 3,665 middle-aged male participants of the Aichi Workers' Cohort Study who were followed-up from 2002 through 2019. Cox proportional hazar ...[more]

PMID: 38281747

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