Microplastics are associated with elevated atherosclerotic risk and increased vascular complexity in acute coronary syndrome patients.

ABSTRACT:

Background

Microplastics, widely present in the environment, are implicated in disease pathogenesis through oxidative stress and immune modulation. Prevailing research, primarily based on animal and cell studies, falls short in elucidating microplastics' impact on human cardiovascular health. This cross-sectional study detected blood microplastic concentrations in patients presenting with chest pain using pyrolysis-gas chromatography/mass spectrometry and evaluating inflammatory and immune markers through flow cytometry, to explore the potential effects of microplastic on acute coronary syndrome.

Results

The study included 101 participants, comprising 19 controls and 82 acute coronary syndrome cases. Notably, acute coronary syndrome patients exhibited elevated microplastic c

SUBMITTER: Yang Y 

PROVIDER: S-EPMC11337598 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature