Efficacy of corticosteroids in patients with acute respiratory distress syndrome: a meta-analysis.

ABSTRACT:

Background

Acute respiratory distress syndrome (ARDS), are respiratory diseases with high morbidity and mortality. Clinical trials investigating the efficacy of corticosteroids in the treatment of ARDS often yield contradictory results. We hereby conducted a systematic review and meta-analysis to investigate the efficacy of corticosteroids in ARDS management.

Materials and methods

We conducted a search for randomized clinical trials (RCT) and observational studies that utilized corticosteroids for patients with ARDS in Web of Science, PubMed, and Embase. The primary outcome was mortality. Risk of bias was assessed using Cochrane or NOS scales. Statistical effect size was analyzed using the Mantel-Haenszel method.

Results

A total of 20 studies, comprising 11 observatio

SUBMITTER: Li G 

PROVIDER: S-EPMC11340212 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature