Comparison of physiological and clinical reactions to COVID-19 and influenza vaccination.

ABSTRACT:

Background

Public reluctance to receive COVID-19 vaccination is associated with safety concerns. By contrast, the seasonal influenza vaccine has been administered for decades with a solid safety record and a high level of public acceptance. We compare the safety profile of the BNT162b2 COVID-19 booster vaccine to that of the seasonal influenza vaccine.

Methods

We study a prospective cohort of 5079 participants in Israel and a retrospective cohort of 250,000 members of MHS selected randomly. We examine reactions to BNT162b2 mRNA COVID-19 booster and to influenza vaccinations. All prospective cohort participants wore a smartwatch and completed a daily digital questionnaire. We compare pre-vaccination and post-vaccination smartwatch heart-rate data, and a stress measure based o

SUBMITTER: Yechezkel M 

PROVIDER: S-EPMC11344792 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature