Combining anatomical and biochemical markers in the detection and risk stratification of coronary artery disease.

ABSTRACT:

Aims

We aimed to test the hypothesis if combining coronary artery calcium score (Ca-score) as a quantitative anatomical marker of coronary atherosclerosis with high-sensitivity cardiac troponin as a quantitative biochemical marker of myocardial injury provided incremental value in the detection of functionally relevant coronary artery disease (fCAD) and risk stratification.

Methods and results

Consecutive patients undergoing myocardial perfusion single-photon emission computed tomography (MPS) without prior CAD were enrolled. The diagnosis of fCAD was based on the presence of ischaemia on MPS and coronary angiography; fCAD was centrally adjudicated in the diagnostic and prognostic domain. Diagnostic accuracy was evaluated using the area under the receiver-operating character

SUBMITTER: Albus M 

PROVIDER: S-EPMC11346366 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature