Canine Distemper Virus: Origins, Mutations, Diagnosis, and Epidemiology in Mexico.

ABSTRACT: This review provides an overview of the canine distemper virus (CDV), a highly infectious pathogen causing severe disease in domestic dogs and wildlife. It shares genetic similarities with the human measles virus (HMV) in humans and the rinderpest virus (RPV) in cattle. The origin of CDV likely involves a mutation from human measles strains, possibly in the New World, with subsequent transmission to dogs. CDV has been globally observed, with an increasing incidence in various animal populations. Genomic mutations, especially in the H protein, contribute to its ability to infect different hosts. Diagnosis by molecular techniques like RT-qPCR offers rapid and sensitive detection when compared with serological tests. Genomic sequencing is vital for understanding CDV evolution and designing ef

SUBMITTER: Rivera-Martinez A 

PROVIDER: S-EPMC11355085 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature