Cost trends of metastatic renal cell carcinoma therapy: the impact of oral anticancer agents and immunotherapy.

ABSTRACT:

Background

Immunotherapy (IO) and oral anticancer agents (OAA) have improved outcomes for metastatic renal cell carcinoma (mRCC), but there is a need to understand real-world costs from the perspective of payers and patients.

Methods

We used retrospective fee-for-service Medicare 100% claims data to study patients diagnosed with mRCC in 2015-2019. We identified initial treatment type and costs (the year after diagnosis) and analyzed differences in monthly and 12-month costs over time and between OAA, IO, and combination groups and the association between Out-Of-Pocket (OOP) costs and adherence.

Results

We identified 15 407 patients with mRCC (61% male; 85% non-Hispanic White). A total of 6196 received OAA, IO, or combination OAA/IO as initial treatment. OAA use decrea

SUBMITTER: Forman R 

PROVIDER: S-EPMC11376369 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature