Feasibility of simulation free abdominal stereotactic adaptive radiotherapy using an expedited pre-plan workflow.

ABSTRACT:

Background and purpose

Improved hounsfield-unit accuracy of on-board imaging may lead to direct-to-unit treatment approaches We aimed to demonstrate the feasibility of using only a diagnostic (dx) computed tomography (CT)-defined target pre-plan in an in silico study of simulation-free abdominal stereotactic adaptive radiotherapy (ART).

Materials and methods

Eight patients with abdominal treatment sites (five pancreatic cancer, three oligometastases) were treated using an integrated adaptive O-Ring gantry system. Each patient's target was delineated on a dxCT. The target only pre-plan served primarily to seed the ART process. During the ART session, all structures were delineated. All simulated cases were treated to 50 Gy in 5 fractions to a planning target optimizati

SUBMITTER: Price AT 

PROVIDER: S-EPMC11382001 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature