Psychiatric, Neurological, and Somatic Comorbidities in Intermittent Explosive Disorder: a retrospective cohort study of electronic health records.

ABSTRACT:

Importance

Intermittent Explosive Disorder (IED) is an understudied psychiatric condition that presents with repeated episodes of impulsive aggression and poorly regulated emotional control, often resulting in interpersonal and societal consequences. Better understanding of comorbidities will allow for enhanced screening, diagnosis, and treatment of patients.

Objective

To investigate prevalence and associations of IED with psychiatric, neurological, and somatic disorders using real-world data.

Design

Matched cohorts of patients with or without IED diagnosis were identified using data from the TriNetX Research Network (until January 31, 2024). Cox proportional hazard models were used to estimate and compare the probabilities of acquiring other diagnoses using patients'

SUBMITTER: Zhang-James Y 

PROVIDER: S-EPMC11419232 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature