LightBox: A multiwell plate illumination system for photoactive molecule characterization.

ABSTRACT: Multiwell plates (MWPs) are the workhorses of the life sciences. However, biophotonics research with MWPs is limited, in part due to the lack of equipment suitable for photo-irradiation of photoactive molecules in a MWP-suitable, high-throughput manner, either commercially or through open-source MWP systems. Here we present "LightBox", a calibrated controllable MWP illumination system with broad applications including screening of photoactive molecules and characterization of photocatalytic chemicals. LightBox is a high intensity, accurately controllable, uniform illumination system designed for MWPs with electronics and a control unit that provides a simple and intuitive interface. LightBox can reach intensities of 0.23 mW/mm² at wavelengths of 405 nm with variance between well

SUBMITTER: Bounds AD 

PROVIDER: S-EPMC11475348 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature