The value of elective neck irradiation in management of esthesioneuroblastoma: a retrospective study based on propensity score matching.

ABSTRACT:

Background

This study aims to assess the clinical efficacy of elective neck irradiation (ENI) in patients with esthesineuroblastoma (ENB), a rare malignant neoplasm, who are clinically node-negative.

Methods

We conducted a retrospective analysis of 178 patients newly diagnosed with ENB at our institution between 2009 and 2021. Propensity score matching (PSM) was employed to compare node-negative patients treated with and without ENI. We extensively examined survival outcomes and treatment failure.

Results

Of the 178 participants, 149 (83.7%) were lymph node-negative and staged in Modified Kadish A-C. 96 patients underwent ENI treatment, while 53 did not. At baseline, patients who received ENI differed from those who did not in terms of radiotherapy technique, staging,

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC11494863 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature