Vitamin D levels in children and adolescents are associated with coronavirus disease-2019 outcomes: A systematic review and meta-analysis.

ABSTRACT:

Background

To explore the relationship between vitamin D levels and risk of SARS-CoV-2 infection and its severity in children and adolescents, and provide a theoretical basis for clinical practice.

Methods

The PubMed, Web of Science, Embase, MEDLINE, and Cochrane Library databases were searched for comprehensive cohort and case-control studies on the association between childhood vitamin D deficiency and the risk and prognosis of coronavirus disease-2019 (COVID-19). The search period was set from December 1, 2019, to December 31, 2023.

Results

The vitamin D insufficiency rate in children with COVID-19 was 80.78% (95% CI, 62.6% to 93.89%), with a deficiency rate of 32% (95% CI: 19.01% to 46.61%). Vitamin D insufficiency was more common in children with COVID-19 than in

SUBMITTER: Wang JG 

PROVIDER: S-EPMC11537629 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature